Cart
sales@molnova.com
iCRT 14
CAS No. 677331-12-3
iCRT 14( iCRT14 | iCRT-14 | iCRT 14 | Wnt inhibitor )
Catalog No. M18982 CAS No. 677331-12-3
iCRT 14 is a novel potent inhibitor of β-catenin-responsive transcription (CRT)(IC50= 40.3 nM in assays of Wnt pathway activity).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 60 | In Stock |
|
| 10MG | 105 | In Stock |
|
| 25MG | 176 | In Stock |
|
| 50MG | 260 | In Stock |
|
| 100MG | 386 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameiCRT 14
-
NoteResearch use only, not for human use.
-
Brief DescriptioniCRT 14 is a novel potent inhibitor of β-catenin-responsive transcription (CRT)(IC50= 40.3 nM in assays of Wnt pathway activity).
-
DescriptioniCRT14 is a potent inhibitor of β-catenin-responsive transcription (CRT) that inhibits Wnt signaling in a reporter assay in vitro (IC50 = 40.3 nM). It inhibits the interaction between β-catenin and T cell factor 4 (Tcf4) in quantitative reporter assays of β-catenin/Tcf4 binding (Ki = 53.51 μM).
-
In Vitro——
-
In Vivo——
-
SynonymsiCRT14 | iCRT-14 | iCRT 14 | Wnt inhibitor
-
PathwayOthers
-
TargetOther Targets
-
RecptorWnt
-
Research AreaCancer
-
Indication——
Chemical Information
-
CAS Number677331-12-3
-
Formula Weight375.44
-
Molecular FormulaC21H17N3O2S
-
Purity>98% (HPLC)
-
SolubilityDMSO : ≥ 29 mg/mL; 77.24 mM
-
SMILESO=C4S\C(=C/c2cc(C)n(c1cccnc1)c2C)C(=O)N4c3ccccc3
-
Chemical Name5-[[2,5-dimethyl-1-(3-pyridinyl)-1H-pyrrol-3-yl]methylene]-3-phenyl-2,4-thiazolidinedione
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1.Gonsalves FC, et al. Proc Natl Acad Sci USA. 2011 Apr 12;108(15):5954-63.
molnova catalog
related products
-
Betaine
Betaine is also known as trimethylamine, and is the quaternary ammonium derivatives of glycine and a class of N-methyl-compound or trimethyl inner salt after the hydrogen of the amino group being substituted by the methyl group.
-
14-Dichlorobenzene
14-Dichlorobenzene is a disinfectant pesticide and deodorant.
-
Benzyl-PEG12-alcohol
Benzyl-PEG12-alcohol is a PEG-based linker for PROTACs, connecting two essential ligands to form PROTAC molecules. This linker facilitates selective protein degradation by utilizing the ubiquitin-proteasome system within cells.
