
iCRT 14
CAS No. 677331-12-3
iCRT 14( iCRT14 | iCRT-14 | iCRT 14 | Wnt inhibitor )
Catalog No. M18982 CAS No. 677331-12-3
iCRT 14 is a novel potent inhibitor of β-catenin-responsive transcription (CRT)(IC50= 40.3 nM in assays of Wnt pathway activity).
Purity : >98% (HPLC)






Size | Price / USD | Stock | Quantity |
5MG | 60 | In Stock |
![]() ![]() |
10MG | 105 | In Stock |
![]() ![]() |
25MG | 176 | In Stock |
![]() ![]() |
50MG | 260 | In Stock |
![]() ![]() |
100MG | 386 | In Stock |
![]() ![]() |
200MG | Get Quote | In Stock |
![]() ![]() |
500MG | Get Quote | In Stock |
![]() ![]() |
1G | Get Quote | In Stock |
![]() ![]() |
Biological Information
-
Product NameiCRT 14
-
NoteResearch use only, not for human use.
-
Brief DescriptioniCRT 14 is a novel potent inhibitor of β-catenin-responsive transcription (CRT)(IC50= 40.3 nM in assays of Wnt pathway activity).
-
DescriptioniCRT14 is a potent inhibitor of β-catenin-responsive transcription (CRT) that inhibits Wnt signaling in a reporter assay in vitro (IC50 = 40.3 nM). It inhibits the interaction between β-catenin and T cell factor 4 (Tcf4) in quantitative reporter assays of β-catenin/Tcf4 binding (Ki = 53.51 μM).
-
In Vitro——
-
In Vivo——
-
SynonymsiCRT14 | iCRT-14 | iCRT 14 | Wnt inhibitor
-
PathwayOthers
-
TargetOther Targets
-
RecptorWnt
-
Research AreaCancer
-
Indication——
Chemical Information
-
CAS Number677331-12-3
-
Formula Weight375.44
-
Molecular FormulaC21H17N3O2S
-
Purity>98% (HPLC)
-
SolubilityDMSO : ≥ 29 mg/mL; 77.24 mM
-
SMILESO=C4S\C(=C/c2cc(C)n(c1cccnc1)c2C)C(=O)N4c3ccccc3
-
Chemical Name5-[[2,5-dimethyl-1-(3-pyridinyl)-1H-pyrrol-3-yl]methylene]-3-phenyl-2,4-thiazolidinedione
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1.Gonsalves FC, et al. Proc Natl Acad Sci USA. 2011 Apr 12;108(15):5954-63.
molnova catalog



related products
-
O-PHOSPHO-L-SERINE
DL-O-Phosphoserine a normal metabolite in human biofluid is an ester of serine and phosphoric acid. Serine is one of three amino acid residues that are commonly phosphorylated by kinases during cell signaling in eukaryotes.
-
L-Glutamic acid mono...
L-Glutamic acid monosodium salt (Monosodium glutamate) is an activator of mGlu1 receptor.
-
FTIDC
FTIDC is a highly potent and selective allosteric antagonist of mGluR1 receptors and shows very weak potency against human and rat mGluR5 receptors.